Gertrude Prideaux-Brune was born in Padstow, the daughter of a magistrate. Her work was exhibited at the London Salon, The Royal Academy, Royal Society of British Artists, Royal Institute of Oil Painters, and at Liverpool's Walker Gallery. Her paintings were published in 'The Yellow Book' in 1895 and 1896. In 1897 she was awarded the RNLI's Silver Medal for Gallantry for her part in a rescue off the coast  of Padstow.

She died in Sunbury-on-Thames.